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The ability to selectively silence genes through a technique called RNA interference (RNAi) has revolutionized biology.
Development and homeostasis require coordinate regulation of neighbouring genes through a process termed locus control.
Riboswitches are RNA elements that control the expression of genes through a variety of mechanisms in response to the specific binding of small-molecule ligands.
For the human datasets we used the 'regulatory circuits' generated by Marbach et al.41 in which regulators were linked with target genes through a series of steps starting from binding motifs in active enhancers using FANTOM5 project data.
Dr Wei therefore ran her 396 genes through a database of all known pathways to see which involved several enzymes encoded by those genes.She found 18 that were involved in addiction to at least one type of drug.
It describes technologies that spread a gene or particular suites of genes through a population.
Sex is a near-universal fact of life that helps spread genes through a population.
Both outcomes are thought to hinge on how loneliness affects the expression of genes through a phenomenon the researchers call "conserved transcriptional response to adversity," or CTRA.
The lupin natives picked up the toluene-eating genes through a process of gene-swapping common among bacteria.
Bacteria and other organisms can even trade genes through a process called lateral transfer, accelerating the spread of traits like drug resistance.
These results indicate that mtUPR activates genes through a CHOP dependent pathway.
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