Your English writing platform
Discover LudwigSuggestions(1)
Exact(8)
Regarding to the quantity of the genes, the probability of pattern division is considered 25% and else is 75%.
According to the amount of genes the probability of patterns' rotation is 25% and their stability is 75%.
Although the selection of this significance level seemed arbitrary and true virulence genes may have lower ranks, our results have demonstrated that, by using this threshold (top-10 genes), the probability of finding a true virulence gene could be improved by up to 10 times compared with random selection of candidate genes.
Since GeneSign performs that test over many genes (usually thousands of genes), the probability to declare that a gene is significant, whereas it is not, increases (multiple testing effect).
If C is the set of all genes, and A and B are two sets of target genes, the probability that their intersection contains z or more genes (under the null model) can be obtained in the R programming language with a call to the hypergeometric distribution function phyper z-1,m,n,k phyper z-1,m,n,k).
Given the gene ontology and annotations of human genes, the probability of occurrence of a GO term t in annotations, p t), is estimated as the number that the term or its descendants are used in annotations divided by the total number of annotations, as In general, more specific terms are less frequently used in annotations and thus have lower probability of occurrence.
Similar(51)
They implemented a Bayesian disease gene predictor that computes for each candidate gene the probability that it is the disease-related gene.
For each interaction in the pathway, we first look at the input genes and determine, for each such gene, the probability of being in a "down" or "up" state (see "gene state" above) We then determine the probability of the materialization of the specific interaction as the joint probability of all needed components (genes) Next, we look at the molecular output of the interaction.
These tests yield for each gene the probability that it has a significantly different ratio than 1.
Therefore, we performed model based clustering and calculated for each gene the probability of belonging to the group of present genes [ 24].
For each gene, the probability whether its reads result from background or from activity above background, was calculated (see Additional file 1: Table S2).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com