Oriented cell division (OCD) and convergent extension (CE) shape developing renal tubules, and their disruption has been associated with polycystic kidney disease (PKD) genes, the majority of which encode proteins that localize to primary cilia.
Benchmarking Universal Single-Copy Orthologs (BUSCO) analysis27 revealed full gene content for 97.5% of PCGs in TM-1 and for 97.3% of PCGs in Hai7124 (Table 1 and Supplementary Table 21); of these genes, the majority were retained in duplicate, largely owing to the allotetraploid nature of the genomes.
Amongst the upregulated genes, the majority of genes belonged to the apoptosis functional category (60%, i in Fig. 10b).
We identified 31 such genes, the majority of which are novel genes or ESTs (Table S16).
This resulted in a list of 270 genes, the majority of which are predicted to encode for multi-transmembrane proteins.
We identified a relatively restricted set of 117 regulated genes, the majority (90) being upregulated by light.
Another set of genes, the majority of which encode DNA repair factors, was significantly down-regulated by acute DSS treatment (Figure 3B).
When analyzing the nucleotide sequences of the fnb genes, the majority of variation laid within the Wr domains in the form of indels, resulting in length differences.
The genome of H.orenii contains a complete set of flagellar genes, the majority of which are clustered between the genes Hore_16540 and Hore_17170.
Extending the classic definition of microRNAs, this large number of new microRNA genes, the majority of which are less conserved than their canonical counterparts, likely represent evolutionarily recent regulators of early differentiation.
We report the identification of over 2,300 taste bud-associated genes, the majority of which have not been described previously in taste tissue, and numerous processes and pathways active in primate taste buds.
