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Although there could be post-transcriptional mechanisms that increase variability in levels of protein for these genes, the levels of mRNA provide a view of the landscape of their regulation.
Out of 10 investigated CYP genes, the levels of CYP2D6 transcripts were among the highest.
In these lines, consistent with the hypothesized silencing of CHY genes, the levels of β-carotene showed significant increases (up to 38-fold).
Compared with the expression levels of relative intestinal stemness genes, the levels were significantly higher in CD44+CD54+ cells, whereas CK20 levels were lower.
Despite the decreased expression of beta-oxidation genes, the levels of long-chain free FAs and triglycerides were lower in the TG than in the WT hearts (Fig 7E and supplementary Table 5).
For 13 genes, the levels of methylation in the tumour tissue exceeded those of the flat mucosa in the same patients, and for 7 genes these differences were statistically significant (P<0.05).
Similar(52)
Expression levels and biological activities of both the genes matched the levels of respective native genes.
For each gene, the level of change in expression is stated as a fold-change.
Every attempt to classify genes above the level of gene family involves a degree of arbitrariness.
However, for both housekeeping genes, the relative levels of target gene expression presented almost the same pattern of changes.
Moreover, variation in GCLC gene influences the levels of MeHgP.
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