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We identified an extraordinary number of differentially expressed genes that support the previously documented histological observations of sebaceous gland hypoplasia, inflammation and epidermal hyperplasia in SKO mice.
We hypothesized that macrophages in the pregnant endometrium would express genes that support placental growth (angiogenesis and tissue remodeling) and that are indicative of a M2 phenotype that signifies a role in modulation of immune responses towards fetal antigens.
Both thymuses expressed genes that support thymic differentiation and function.
In E. coli, for example, ydiI is not colocated with the genes that support menaquinone synthesis.
The pkD46 plasmid carries the lambda Red genes that support homologous recombination.
Identification of other immuno-metabolic genes that support cardiometabolic GxEs is intriguing but has not been explored sufficiently.
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The 161 genes of the maxspe alignment were individually analyzed in order to estimate the proportion of genes that supported each of the six alternative topologies shown in Figure 4.
We had information about these three genes that supported their inclusion in our analysis.
We characterized the genes that supported each hypothesis, and found that differences in rates of evolution or in amino-acid compositions could not explain the presence of two dominating phylogenetic signals in the alignment.
We characterized the genes that supported each of these two hypotheses, and found that differences in rates of evolution or in amino-acid compositions could not explain the presence of two incongruent phylogenetic signals in the alignment.
Other metagenomic studies that compared the metabolic potential of microbial communities from differing environments, e.g., agricultural soil, sea surface, and deep-sea whale carcasses, have shown noticeable differences in the enrichment of various genes that supports microbial lifestyle in their niche [4], [5].
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