Indeed, of the 16 immunodeficiency viruses the researchers looked at, all but five had nef genes that removed TCR-CD3 from the cell surface.
Oxidative damage is an important factor in prostate carcinogenesis, and overexpression of human MutT homolog (hMTH), a repair gene that removes oxidative damage, is a molecular marker of cellular oxidative stress.
At its meeting in Groton, Pfizer presented long-awaited data studying torcetrapib in 437 patients who have a faulty version of a gene that removes cholesterol from the body.
To obtain HSV-2 viruses that varied in their level of attenuation, deletions were introduced into the ICP0 gene that removed none, one, or all of ICP0's conserved regions (Fig. 1A, 1B).
Van Buchem's disease is a similar disorder with generalized hyperostosis and a 52-kb deletion downstream (35 kb) of the SOST gene that removes a SOST-specific regulatory element [30], [31].
Further studies by Van Hul et al. [ 15] and Balemans et al. [ 16] revealed that VBCH was caused by a 52-kb deletion approximately 35 kb downstream of the SOST gene that removes a SOST-specific regulatory element.
With Dr. Maki Nakayama, he showed that this epitope is absolutely essential for diabetes development in the NOD mouse by engineering NOD mice that no longer express the native insulin genes but rather a mutated insulin gene that removes the antigenicity of this epitope and in turn prevents diabetes (75).
HDACs are important regulators of gene expression that remove acetyl groups from histones enzymatically.
These four genes encode enzymes that remove 'reactive oxygen species' from cells.
The PDR1 and PDR3 genes regulate ABC transporters that remove xenobiotic substances from the yeast cytoplasm.
Supporters of enhancement often point out that we believe that it should be permissible to carry out genetic interventions that remove genes for specific genetic diseases.
