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Of particular interest, the researchers reported, the analysis identified families of genes that link the platypus to reptiles (like those for egg-laying, vision and venom production), as well as to mammals (antibacterial proteins and lactation).
Finally, we constructed global co-expression networks of ESCs, which were dominated by a few highly-connected genes (hub genes) that link the less-connected genes to the system.
The scale-free property, a common features among biological networks [18], [21], [33], [34], suggests that the topology of the ESC co-expression networks is dominated by a few highly-connected genes (hub genes) that link the less-connected genes to the system.
Our results indicated potential genes that link to TNBC migration.
In SPIA, more influence is placed on genes that link out to many other genes.
We show that these elements we call gateway nodes represent genes that link critical functions at different stages of development.
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On the other hand genes that linked to responses to external stimuli like immune response or sensory perception show elevated levels of sequence variation, segmental duplications and retrotransposition as compared to the genomic average [25].
Among them, optineurin is a gene that links particularly to normal pressure glaucoma, a subtype of POAG that accounts for approximately 30% of the POAG cases [6].
Networks commonly have one or more core (or 'hub') gene that links to many others within the network.
CO is an important gene that links the circadian clock to flowering [ 15], and it induces the transcription of FLOWERING LOCUS T (FT) to promote flowering [ 11, 16].
They also show that Irx3-deficient mice have reduced body-weight, and thus argue that IRX3 is a prime candidate to be the causative gene that links the risk SNPs to obesity [ 4].
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