We identified 7 genes specific for survival of MPSNT cells, including MEIS1.
For Fig. 1i, we identified the top 50 putative marker genes specific for each lineage inferred from transcriptomes based on both relative differential expression (FC) and absolute expression levels (normalized read counts).
One composed by genes specific for miR-34a activation ("34a-specific", 2039 genes) and enriched for pathways controlling cell cycle, checkpoints, E2F, and MYC targets (Supplementary Fig. 3c), which explain the anti-proliferative role of miR-34a in progenitor cells.
In particular, MYB family transcription factors are emerging as central players in the coordinated activation of sets of genes specific for the anthocyanin and tannin pathways.
During differentiation, transcript levels of pancreas‐specific transcription factors (i.e., Pdx1, Pax4) and of genes specific for early and mature β cells, including insulin, islet amyloid pancreatic peptide, somatostatin, and glucagon, are upregulated.
Chromophobe RCCs express FOXI1-driven genes that define collecting duct intercalated cells, whereas HNF-regulated genes, specific for proximal tubule cells, are an integral part of clear cell and papillary RCC transcriptomes.
It is therefore difficult to select GPAT, LPAT and DGAT genes specific for CB biosynthesis directly from plants.
Besides, by replicating the susceptible genes specific for the East Asian, 6 loci showed significance in our Chinese samples, with KCNQ1 showing the strongest association with T2DM [19].
They included genes specific for the neural crest cells, such as tfap2 (Fig. 4D).
Genes specific for B cells (CD79A and CD79B) were differentially up-regulated in MAT vs SAT.
To identify genes specific for these groups, hierarchical clustering was employed, using the average distance method.
