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In Saccharomyces cerevisiae, the Tor proteins regulate the transcription of genes sensitive to the quality of available nitrogen and carbon sources.
As an additional control experiment, we transfected U2OS-Δα-Nuc cells with luciferase reporter genes sensitive to cAMP (CREB), Ca2+ (NFAT) and glucocorticoid hormone receptor (GR) signaling.
In order to identify target genes sensitive to the drug treatment we selected seven genes that have been shown to be expressed at defined stages of spermatogenesis.
Body nutrient homoeostasis is under the control of hormonal and metabolic adaptations and involve changes in the expression of genes sensitive to dietary and nutritional conditions (Waterlow, 1981 FAO).
By analyzing the gene expression profile of these cell lines on an Aplied Biosystems Mouse Genome Survey Microarray, we detected 223 genes modified by estradiol; whereas Wnt3a modified 303 genes, sensitive to Δ56LEF-1 (see Table 1, containing only the annotated sequences).
Each peak represents co-expressed genes sensitive to Pros expression.
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In the course of his research, Guarente says, he came to believe that there may be a particular gene, sensitive to the metabolic reactions of starvation, that would trigger a chain of life-extending, energy-preserving biological maneuvers.
Alternatively, a deletion either within or encompassing a gene sensitive to haploinsufficiency can have the same effect as a disruptive point mutation within the gene.
AlaS, encoding alanyl-tRNA synthetase, acts as an autorepressor of the alaS gene, sensitive to the concentration of alanine in bacterial cells [ 69].
These results suggest that PsPINs and PsAUX1 are auxin-inducible genes, and that the expression of PsPINs and PsAUX1 genes is sensitive to gravistimulation.
The subset of genes most sensitive to alignment method in real data consists primarily of closely related gene families and protein-coding genes with retrotransposed pseudogenes.
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