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CGOB was interrogated for evidence of clustering of genes (i.e. lying within 10 genes of one another on the same chromosome) in the 99 nonredundant pathways.
When the predictive genes of one platform were utilized on the opposing platform, however, much lower accuracy was obtained.
Most network-based gene prioritization methods, including this one we have developed here, were created on the basis that causative genes of one disease may tend to locate closely in the network [ 6, 10].
The identification of variants was based on one trait and for variants in genes of one specific molecular pathway.
The rally was also fueled by a jump in biotechnology stocks after the Celera Genomics Group said it completed sequencing the genes of one person.
However, both approaches only partially solve the problem and cannot link all the functional genes of one microbe to its phylogeny.
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Therefore genes of one-to-one orthologs also should be subject to functional constraints.
Expression changes in genes of one-carbon and lipid metabolism were particularly significant in FASD Mthfr+/− mice.
This manipulation occurs in a biotech lab by a geneticist taking a specific gene of one species; let's say a flounder, and inserting it into another, such as a tomato, or inserting a bacterium into a corn seed to make it resistant to certain pests.
V600E mutation was discovered in the BRAF gene of one patient.
Of the 128 SNPs examined, only two in one gene of one strain were not confirmed by Sanger sequencing.
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