These associations were also selective (p<0.01), as assessed by repeated testing of the Ingenuity database with random gene lists of equivalent or variable sizes of selected genes (60 to 200 genes).
To assess whether the association of the identified biological modulators with the top networks was specific (p<0.01), we resampled the Ingenuity database 100 times of with random gene lists of equivalent sizes.
Consequently, equivalent exons are quite limited in the 5'-terminal compared to the remaining regions of the gene (number of equivalent exons in the three regions 4 10 9) (see Figure 3).
The intersection of these two sets contains 25 genes, which is a much larger number of genes than randomly expected using simulations of equivalent gene sets (empirical P < 0.001).
Thus, it should be able to draw conclusions about the purpose of equivalent genes in humans.Another paper discusses a new form of gene mapping.
While, as expected, the reads mapped to the 5'-UTR + CDS of both genes are equivalent, the number of reads containing sequences belonging to the 3'UTR of HSP70-II gene (LmjF.28.2770) was 6,24 fold higher than the number of reads corresponding to the 3'UTR of HSP70-I gene (LmjF.28.2780), even though the 3'-UTR lengths are very similar (1096 and 1084 nucleotides, respectively).
Cementing this point, it was shown that, using the same dataset and similar but non-identical methodology, many different 70-gene poor prognosis signatures of equivalent accuracy can be derived out of the original data [ 19].
The C × E population shows a strong variation in the onset of tuber formation (early--late) and to allow a comparison of gene expression in tubers of equivalent physiological state, a choice was made to extract RNA of 'mature' tubers harvested several weeks after haulm killing.
The problem is that to many people saying that something is the result of genes is equivalent to saying that something is fixed, determined, and that there isn't anything you can do about it.
In general, the 3 natural allotetraploids (Maxxa, Tx2094, and G. tomentosum) exhibited a consistent expression pattern (i.e., approximately equal number of genes in equivalent categories).
