Knocking down such genes not only blocks autophagy but also renders apoptosis defective, making the interpretation of autophagic roles unreliable.
An engineered yeast strain overexpressing ERG10, hbd, and tesB genes not only exhibited enzyme activities of AACT, ACR, and HBT, but also produced S-3HB from ethanol.
Expression of frp with the lux genes not only stabilized but also enhanced bioluminescence to levels approaching 9.0×105 times above background.
Shaped through aeons of evolution, our genes not only make us what we are but hold in their minute beings the promise, or threat, of what we shall become.
For the hyper-accessible genes, not only levels of sense (Fig. 6b) but also antisense transcripts were significantly higher than the genome median (P-value=5.9 × 10-5; Fig. 8a).
Successful pathogens use effector molecules, encoded by Avr genes, not only to suppress host immunity but also to manipulate host cellular mechanisms for their own benefit, leading to effector-triggered susceptibility (ETS 28.
What scientists learned was that if they designed a double-stranded RNA corresponding to an animal or plant cell's own genes, they could get the cells to silence those genes, not only those of a virus.
It is therefore critical to understand the biological mechanisms controlling the segregation of mitochondrial genes, not only in somatic tissue, but also in the germ cell lineage, since the latter is the means of transmission of pathological mutations across generations.
Moreover, Mr. Berio honors those genes not only in the solo part but in the gorgeous and poetic sounds he conjures from two ensembles and three percussionists behind the violist, here members of the Vienna Radio Symphony conducted by Dennis Russell Davies.
Therefore, pinpointing the methylation fingerprints (5′CpG island methylation) of potent DNA repairing genes not only shows the specific attributes of locally advanced breast cancer but also provides important insight into the mode of therapy to be used by clinical oncologists.
Implementation of a single assay to effectively detect mutations and amplifications in clinically relevant genes not only improves the efficiency of the workflow within diagnostic laboratories but also increases the chance of detecting (rare) actionable variants for a given tumor type that are typically missed in routine pathology.
