Collaboration between mitochondrial & nuclear genes is required for pollen function.
During limb development, coordinated expression of several Hoxd genes is required in presumptive digits.
Wieczorke, R. et al. Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae.
Laufs, P., Peaucelle, A., Morin, H. & Traas, J. MicroRNA regulation of the CUC genes is required for boundary size control in Arabidopsis meristems.
In this assessment seed genes were chosen at random, however careful selection of seed genes is required to obtain more reliable prediction of target genes.
The use of a number of independent genes is required to resolve phylogenetic relationships, especially for groups displaying low polymorphism.
Thus, development of quick, easy and efficient means to systemically analyze the functions of all genes is required in the post-genome era.
Therefore, the development of algorithms that possess the advantages of RJMCMC methods and are also efficient and easy to follow for selecting disease-associated genes is required.
For biotechnological and physiological studies often co-expression of recombinant genes is required, however for C. glutamicum no vector for the independent co-expression of two genes was described.
Dysregulation of methylation at H3K27 may have important consequences in cancer, as demethylation of H3K27 at HOX genes is required for proper differentiation.
A peptidyl-prolyl cis trans isomerase from Cryptococcus (Ess1), non-homologous to the above two genes, is required only for virulence (Ren et al. 2005).
