Sentence examples for genes indispensable for from inspiring English sources

CS is caused by mutations in two genes indispensable for TC-NER, CSA and CSB.

As anticipated, control siRNAs targeting genes indispensable for cell survival (UBC, PLK-1) induced prominent cell killing (without CTLs; x-axis; Fig 2C E).

These results support our hypothesis that the genes in cluster 1 likely include candidate genes critical for tumorigenicity and that the genes in cluster 4 likely include candidate genes indispensable for metastasis.

The genes indispensable for motor neuron survival may be identified in the future by comparing the numerous abnormally spliced genes reported in SMA with the same genes in ALS.

Previous studies have proposed that PML-RARα acts as a strong transcriptional repressor for target genes by directly binding their promoter regions, which are thought to include genes indispensable for myeloid differentiation and apoptosis [ 7, 8].

Possible alternative but not mutually exclusive explanations include MSUC affecting genes indispensable for male meiosis or a failure of MSCI due to asynapsis caused primarily by meiotic gene mutations (Mihola et al. 2009; Mahadevaiah et al. 2008; Burgoyne et al. 2009; Hayashi et al. 2005).

Recently, a method for predicting accurate margins of SMB gene clusters by analyzing the co-expression of neighboring genes has been reported, with the condition that the gene indispensable for the SMB gene cluster is identified using the known sequence of the core gene.

However, after this report it was noted that the genome lacks the acetyl-CoA synthase gene, indispensable for this pathway, and the CODH gene is clustered with ECH genes, suggesting that C. subteraneus subsp. tencongensis has the capacity for hydrogenogenic carboxydotrophy [ 13].

Essential genes are indispensable for the survival of living entities [ 1, 2], and the functions of proteins encoded by these genes are considered to be the foundation of life [ 1– 3].

Ubiquitous inactivation revealed that both genes are indispensable for embryogenesis albeit in different ways.

Gene targeting studies in mice have shown that DNA mismatch repair (MMR) genes are indispensable for SHM, CSR, and lymphoma suppression of B cells [9], [22], [23], and that even MMR haploinsufficient mice exhibit subtle phenotypes [9], [23].