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AP-1 dimers of distinct composition preferentially enhance transcription of a wide variety of target genes, including other AP-1 family subunits [15].
Each manipulated TF modifies the expression of many downstream target genes, including other TFs, which can in turn activate or repress genes even farther downstream.
In M. domestica, the SWEET genes, including other sugar transporter genes, are involved in sugar accumulation in sink tissue and the concentration of sugars were positively correlated with the SWEET gene expression [ 39].
We propose that one of the Cbf genes belonging to the central cluster (Cbf-12 or -14) may serve as a key regulator of other genes including other Cbf genes.
Global adoption of the proposed H5 clade nomenclature and its expansion to other influenza lineages and genes, including other animal influenza virus subtypes, will benefit human and animal influenza research and public health.
DREB1/CBF proteins bind to DRE/CRT elements in enhancers and activate transcription of target cold-inducible genes, including other transcription factors, and thus bring about transcriptomic and metabolomics changes, which eventually cause cold stress responses [ 15, 38].
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If these regulated genes include other hub genes, the regulatory "ripple effect" can be significant.
The down-regulated genes included other TGFβ superfamily members: BMP7 (−6.436) and GDF9 (−1.865).
Other non-cancer diseases implicated with many genes include other complex diseases including diabetes and rheumatoid arthritis.
In addition, our application performs downstream statistical analyses to identify features that are associated with gene variation, including other query genes (i.e. gene co-variation), taxa, clinical variables (e.g. inflammatory bowel disease and diabetes) and average genome size.
Besides the prodrug therapy, there are also other options of SC gene therapies including other therapeutic agents such as interferon- β (IFN- β), interleukin (IL -2, IL -2 and IL-72, and IL-12 [ 2].
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CEO of Professional Science Editing for Scientists @ prosciediting.com