Unexpectedly, these genes in general also showed downregulation (Fig. 5b).
Integrated classification models combining sub-sets of genes, in general, degraded classification performance.
As seen from the results in Table 1, pathways that contained fewer genes in general indicated no correlation in branch length between the genes.
The 3R polymorphisms observed in this study suggest that these genes in general may be subjected to negative/purifying selection pressure.
However, we also observed a high frequency of reduced expression amongst miRNA target genes in general, regardless of the expression levels of their predicted effecter microRNAs.
Combining the idiosyncratic aspects in the GapC1 phylogeny with "lateral mobility" of GAPDH genes in general, we propose a new hypothesis for GapC1 evolution.
This suggests that the genes involved with oxidative stress response are more highly conserved across domains than archaeal genes in general.
On the contrary, complex genes, dosage sensitive genes and highly connected genes in general, show very low dN/dS ratios, irrespective of whether they overlap CNVs or not.
Because duplicated genes in general degenerate within a few million years [3], these data thus indicate that nGPCR gene duplicates have a greater probability of escaping gene loss after WGD than average genes in the genome.
The micro-array data for D. melanogaster gene expression after infection with bacteria and fungi [25] showed that there was no significant difference in induction between clustered and non-clustered immune genes in general (Fig. 3, Tab. 2).
Previous studies have demonstrated that some genes were characterized by their variable levels of methylation in different tissues, and undermethylation in these genes in general correlated with tissue-specific gene expression [16], [41], [42].
