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For example, it can be used to search for the co-expression of genes in components of interest or to identify genes that might mark a particular structure.
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Further, similar observations as in the first two scenarios can be made from results for Scenarios 4 and 5 (Supplementary Figs S2 and S3), where the effect sizes are random across genes in component studies.
From these cellular components, we identify the ones with a statistically significant Spearman rank correlation coefficient between profile vectors whose components correspond to the vertex betweenness centrality values of the genes in cellular components.
Consistent with this idea, there is an altered expression of developmental genes and an incomplete overlap among dysregulated genes in different components of the cohesin apparatus.
The function of genes in "the components of melanosomes and their precursor" and 'Eumelanin and pheomelanin' are melanin synthesis and the switch between eumelanin and pheomelanin [ 15].
In the present study, zinc exposure did not cause changes in gene expression in components of cardiac electron transport proteins; however, it did increase the expression of genes involved in mitochondrial fatty acid metabolism.
The mean expression of the genes in mixture component one was between a half and a third of the mean expression of the genes in mixture component two.
BaP induction of many genes in the component pathways indicated in Figure 7 suggests that this model likely applies also in Oikopleura.
38 Various genes in this component connected the 25(OH D system to the IFNB-1b system (e.g., LTF and ELANE).
A considerable number of genes in this component are targets of ubiquitination (UBC) and sumoylation (SUMO1 and SUMO2) possibly causing their inactivation.
There were 467 DEGs and 255 up-regulated genes in GO component ontology, 1,040 DEGs and 423 up-regulated genes in GO function ontology, and 568 DEGs and 240 up-regulated genes in GO process ontology.
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