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The blocked 735 reactions linked to 533 genes, formed a platform for guided gene deletions in B. subtilis to generate simplified host strains.
The most highly induced genes formed a cluster that contained putative outer membrane proteins analogous to the starch utilization system identified in the prominent human gut symbiont Bacteroides thetaiotaomicron.
However, eight GRIN2B genes and eight fish GRIN2C genes formed a sister clade with their respective tetrapod orthologue.
Five of the aforementioned six genes formed a cbi operon (APJL1657-1652) encoding a putative nickel and cobalt periplasmic permease system, which may affect the total urease activity in A. pleuropneumoniae [44].
DNA replication genes formed a distinct co-regulated cluster that shared nearly identical peak times in late-G1 in advance of commitment to chromosome replication in S phase (Figs. 3B; 4D).
Moreover, these three genes formed a tandem duplication cluster.
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However, the pear DAM genes formed an independent subclade.
In each CRISPR type, the Cas genes formed an array toward the CRISPR locus.
Genes form a biological blueprint that is largely reactive in nature, and the TCF7L2 gene was apparently quiescent during most of our evolution.
They showed that several proteins expressed by the mutated genes form a complex that cooperates with a cancer-causing protein to promote cancer-cell survival3.
(ii) We next found that 75% of the expressed genes form a single connected subgraph (connected component in graph theory19) (Sprefr.cort = 2, 001, Fig. 1C).
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