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The genetic analysis using TagSNPs in the five genes included in the adiponutrin gene family revealed that some variants within these genes exert a weak but significant effect on obesity in children and adolescents.
The present study highlights that common variants of inflammatory cytokine genes exert a modest effect on risk of DN and a combination of risk alleles confer a substantial increased risk of nephropathy in type 2 diabetes among Asian Indians.
Vertebrate Hox genes exert a fundamental role in hindbrain formation and segmentation [ 17, 18].
Genetic research regarding myopia has traditionally been guided by the assumption that genes exert a direct effect on the trait.
All too often people assume that genes exert a deterministic effect and that nothing can be done to help a child whose impairment has a constitutional origin.
These four genes exert a high degree of flux control over the cell cycle, and their sequential deletion had significant effects on growth rate.
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This suggests that a large proportion of genes exert an intriguing, yet uncharacterized, function during petal morphogenesis.
Overexpression of these genes exerted a positive impact on the leavening activity of baker's yeast.
A combination of IL-2 and TK genes exerted a more potent therapeutic outcome in a metastatic carcinoma model, and induced antitumor immunity [ 1].
Second, simulation analyses of transcriptional regulatory networks have shown that genes exerting a high degree of control over other genes, or those that are less regulated by other genes, are expected to be more strongly affected by selection [ 33].
Second, TFs are multifunctional and typically cooperate to activate or repress genes, exerting a more complicated effect on transcriptional regulation than the assumption of a simple linear sum of TF activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com