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Although several strategies introduce sequence diversity, the likelihood of identifying proteins with novel functions is increased when the library of genes encodes for folded and soluble structures.
A majority of the genes encodes for proteins that are involved in particular developmental functions, such as transcriptional regulation and signal transduction (Fig. 2C).
About half of the diatom genes encodes for proteins of unknown function, suggesting that many regulators of central processes in diatom biology remain to be identified.
Functional analysis by IPA and KEGG demonstrated that 25% of the selected genes encodes for protein involved in mitochondrial oxidative phosphorylation system.
Moreover, it should be noted that the majority of strain-specific genes encodes for proteins of unknown function, i.e. the functional significance of the majority of differences is thus uncertain.
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It coincides with the AI genes encoding for DNA polymerase I and receptor-like protein kinase.
The genes encoding for PRR were upregulated as early as 6 h after infection.
Furthermore, this strain has a changed transcription profile concerning genes encoding for hydrolases and enzymes associated with degradation of (hemi celluloses.
In mammals two genes encode for somatostatin-related peptides, somatostatin 14 and 28, and cortistatins, respectively.
Mutations in genes encoding for structural proteins of immunological importance may have practical implications.
Some genes encoding for these enzymes have been cloned and used to construct "engineering bacteria".
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