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Lymphopoiesis requires the activation of lineage-specific genes embedded in naive, inaccessible chromatin or in primed, accessible chromatin.
For the first time, humans can intervene in changing our genetic code — and the disease genes embedded in it — that took biological evolution 3.5 to 4 billion years to produce.
Genomics and proteomics approaches generate distinct gene expression and protein profiles, listing individual genes embedded in broad functional terms as gene ontologies.
However, it is unknown whether there is a coordinated regulation of the genes embedded in these regions in normal cells and in early stages of tumor progression.
The genes embedded in these regions showed a dynamic and autonomous regulation during mouse intestinal cell differentiation, indicating that, in the framework considered here, the coordinated regulation in LRES is restricted to cancer.
We analyzed the magnitude and nature of nucleotide variation, with the objective of distinguishing likely candidates for regulators of SI from other genes embedded in the S-locus region.
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We seem to have a taxonomical gene embedded in our makeup; but if you are compelled to name and to categorize, be as basic as you can.
To test this inference, an ICP0-expressing adenovirus vector, Ad-ICP0, was compared to a control vector, Ad-n212 (Table 2), for its capacity to stimulate the expression of the ICP0−GFP reporter gene embedded in the native LAT-ICP0 locus of HSV-1 0−GFP.
This missing function could be accomplished by the conserved hypothetical gene embedded in the hdr locus of sulfur oxidizers.
To ascertain the common role of yeast JmjC demethylases in regulating telomeric silencing, we performed silencing assays in cells containing a URA3-reporter gene embedded in the telomere-proximal regions on the left arm of telomere VII (TEL07L).
While insertion of retrotransposons into other retrotransposons is well documented from other regions of maize as well as other plant genomes, finding an intact gene embedded in a retroelement was unexpected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com