Using EASE, we classified the 39 genes comprising the LPA signature into two groups: cellular localization and molecular function.
The genes comprising the top doublets also provide easily interpretable results, as compared to other methods like SVM.
The protein kinase complement of the human genome (kinome) includes 518 predicted genes, comprising the third-largest gene superfamily [5].
Genes comprising the MAPK pathway, BRAF, MEK1 and MEK2, were systematically scanned for mutations in 15 ovarian cancer cell lines using bidirectional direct sequencing of all exons.
Further, the presence of ten distinct genes comprising the PE-PPE domain as paralogs in M. tuberculosis strain H37Rv is an example of gene duplication.
Further research will be required to characterize allele frequencies in distinct populations, and to identify new mutations in the hundreds of genes comprising the molecular hearing apparatus.
A comparison of the genes comprising the two networks revealed 20 overlapping genes, which hold high priority as candidates for epilepsy.
Transcription factor analyses were performed to look for the enrichment of transcription factor targets in the genes comprising the acquired resistance signature (BRB-ArrayTools).
Although our data are only correlative, they suggest further examination of the mechanism by which the genes comprising the molecular circadian clock in F. fragum and other cnidarians may regulate diel behaviors like tentacle expansion and retraction.
However, since at this time there are no known genes comprising the photoperiodic switch in natural populations of any animal, we fully expect that candidate loci in W. smithii might have no annotated ortholog in D. melanogaster.
This allowed mapping of the 3,067 significant genes comprising the gene expression profile of PBMC of S. aureus-infected patients based on the Affymetrix gene probes to their corresponding 1,521 gene probes on the Illumina platform.
