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It is possible that the DNA methylation polymorphism in these genes causes a subtle difference in the degree of trophoblast invasiveness among individual human placentas.
Therefore, in both mouse and zebrafish, depletion of Popdc genes causes a muscle defect.
Recombination of these incomplete cDNA molecules with genes causes a preferential loss of introns at the 3' sides of genes.
A mutation at the loci of each of those genes causes a decrease in longevity except for Tor, whose inhibition increase longevity [ 63].
We show that RNAi of these genes causes a wide range of regeneration phenotypes, and that the pioneer transcription factor FoxA, which functions in many organisms to specify endodermal organogenesis, is required for regeneration of the planarian pharynx.
It may be either negative or positive, where the combination of mutations in two genes causes a greater or lesser phenotypic consequence, respectively, than expected from individual mutations (Dixon et al. 2009).
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Removal of Hox genes causes an increased number of digits (up to 14) in mice, demonstrating a Turing-type mechanism in the development of the hand.
Predictably, mutations in ciliary genes cause a wide range of human diseases such as male infertility and blindness.
The cobU and cobS genes caused a slight increase in the production of vitamin B12.
To investigate whether genetic polymorphisms in the resistin and adiponectin genes cause a predisposition towards polycystic ovary syndrome (PCOS) in a South Indian women population.
Hereditary spastic paraplegia (HSP), characterized by relatively selective axonal degeneration, is a genetically heterogeneous condition, with more than 50 genes causing a similar neurologic phenotype.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com