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Genes can play only the indirect role of encoding and transmitting the adaptive features that organisms need to compete successfully.
Here we argue that trade-off-like and conditional effects of genes can play central role in this phenomenon and in determining longevity.
Various other factors, like your genes, can play a role in the development of melanoma — which is the most dangerous form of skin cancer.
Of course, our genes can play a role in how strong or poor sight is as well.
In fact, MHC genotype has been proposed as a magic-trait in stickleback [12], partly because immune system genes can play a dual role in both parasite resistance and mate choice [15].
Microsatellite within genes can play vital role in gene regulation for controlling a particular trait.
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siRNA sequence designed against survivin anti-apoptotic gene can play this role if carried to the cytoplasm.
Nuclear architecture and the relative position of a gene can play roles in the regulation of its expression.
Thus, it is reasonable to speculate that in most cases a single gene can play a critical role in a key improvement transition.
Given that sik1 is specifically involved in cardiomyogenesis, we can speculate that this gene can play a role in CHDs observed in Down syndrome patients, opening new avenues in the understanding of the biological pathways involved in this severe disorder.
In addition, mutations or amplifications of Pfmdr-1 gene can play a significant role in P. falciparum resistance to diverse antimalarials such as mefloquine, quinine or artemisinin derivatives [10].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com