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Although several genes can mediate responses to alternate DR regimens, no single genetic intervention has recapitulated the full effects of DR, and no unified system is known for different DR regimens.
However, whether these sets of target genes can mediate the glucocorticoid response will require further study.
Most of the SAUR genes can mediate auxin-induced cell elongation during the morphogenesis of multiple organs [ 46, 47].
In addition to these transcription factors and pathways, it is known that several enzyme-related genes can mediate mucus-producing cell differentiation [ 38- 40].
The data from this study indicate that class 1 integrons and IS CR elements linked to sul2 genes can mediate TMP/SMX resistance in S. maltophilia and are geographically widespread, findings that reinforce the need for ongoing resistance surveillance.
Given our results, it is difficult to accept that the (barely perceptible) changes in the levels of H3K4me3 produced during the activation of transcription in the up-regulated genes can mediate the downstream effects affecting the acetylation state of H3 in a short time when the opposite is much more likely.
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Using small interfering RNA (siRNA) screening, investigators are also currently working to identify additional HR repair genes that can mediate synthetic lethality with PARP1 inhibition [23].
EGR1 is an early response gene and can mediate cellular responses to mitogens and growth factors.
It confirms that gene conversion can mediate homogenization of reiterated sequences in higher eukaryotes.
This study is the first to implicate PUMA as an IRF-1 regulated gene that can mediate apoptosis in cancer cells.
The transcription factor IRF3 can mediate cellular antiviral responses by both inducing antiviral genes and triggering apoptosis through the activation of RIPA.
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