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Genetic changes in influenza surface and internal genes can alter viral fitness and virulence.
For instance, it has been reported that DNA methylation in the body of genes can alter chromatin structure and reduce transcriptional elongation [25].
Many other genes can alter SCN responses.
Specific mutations in the capsid genes can alter antigenicity and neutralization properties of enteroviruses.
Genes can alter sensitivity to environmental risks (gene environment interaction), for example, environmental toxins or psychosocial adversity.
Therefore, the same posterior Hox genes can alter cell ingression and axis elongation with a similar collinear trend.
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However, it has recently been demonstrated that common genetic variations in deiodinase 1 (DIO1) gene can alter deiodinase function, resulting in an alteration in the balance of circulating FT3 to FT4 [ 18].
The network displayed in Figure 1 clearly reveals the massive scale of influence that cigarette smoke, as an environmental variable, exerts over the lymphocyte transcriptome; however we are unable to determine which genes are directly influenced by smoke exposure, given that alteration of the expression level of one gene can alter the transcription of other genes in these networks.
Changes in the expression of a single gene can alter levels of other genes and provide information on developmentally regulated gene expression pathways.
That a single gene can alter such complex social behavior is surprising, says Wynshaw-Boris.
The insertion of an enhancer sequence in the vicinity of an endogenous gene can alter the transcriptional pattern of the gene, resulting in a mutant phenotype.
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