Sentence examples for genes binding to from inspiring English sources
Our study revealed promoter regions corresponding to 217 genes binding to TEL-AML1 and being differentially expressed on mRNA level after TEL-AML1 induction.
A single transcription factor can regulate the expression of hundreds of genes, binding to a subset of commonly occurring DNA regulatory motifs in a sequence-specific manner (FitzGerald et al. 2004; Yang et al. 2007).
Both hormones stimulate transcription of target genes binding to their nuclear receptors that interact with specific responsive elements (estrogen and thyroid hormone response elements, i.e., ERE and TRE, resp). in the regulatory regions of the gene.
Therefore, MeCP2 was predicted to be a global repressor of transcription of genes by binding to methylated gene promoters and recruiting transcriptional repressors to silence gene expression [ 30].
Runx genes regulate transcription of target genes by binding to a variant of the consensus binding site RCCRCA (R = purine).
DOI: http://dx.doi.org/10.7554/eLife.02042.015 To confirm that the main function of Chd1 is at processive genes, Chd1 binding to stalled or processive genes was addressed.
ARFs are key regulators of auxin-modulated gene expression [ 58] that activate or repress target genes by binding to the promoters of early auxin response genes.
Under these conditions, Mig1p is predominantly in the dephosphorylated state and translocates into the nucleus [ 17, 19] to repress genes by binding to the URS of various genes.
The gene battery concept predicts that upstream transcription factors coordinate the expression of target genes through binding to similar cis-regulatory elements in the target genes.
Furthermore, HsfA2 in Arabidopsis has been shown to regulate the expression of several sHSP genes by binding to HSEs in the target gene promoters (Schramm et al. 2006).
TFs are proteins that relay cellular signals to their target genes by binding to the DNA regulatory sequences of these genes and modulating their transcription [ 12].
