Sentence examples for genes at sites from inspiring English sources

The presence of multiple genes at sites of transcription (transcription factories) has been postulated to act as a stabilising force on chromosome architecture [39] and inhibition of transcription can cause some retraction of chromatin loops [40].

The human immunodeficiency virus (HIV) integrates preferentially into actively transcribed genes at sites with transcription-associated histone modifications.

H2A.Z is co-localised with other active histone modifications at the 3′ end of genes, at sites that match the start sites of non-coding transcripts transcribed in the antisense orientation relative to the sense protein-coding genes.

In summary, Stat6 binds near lysosomal genes at sites marked by active chromatin configurations, and at several lysosomal genes Stat6 contributes to the establishment or expansion of these markers.

The mechanisms that control the disengagement of FACT from transcribed genes are yet to be defined, but it appears that these are to a certain extent gene-specific because yFACT has been shown to disengage from certain genes at sites downstream from the polyadenylation (pA) sites and at other genes at sites upstream of the pA sites (Kim et al. 2004; Mayer et al. 2010).

Upon activation, the HIF-1 complex binds to target genes at sites containing the core recognition sequence 5′-RCGTG-3′, also known as the hypoxia regulatory element (Minchenko et al, 1994), which leads to the upregulation of genes involved in angiogenesis (VEGF), glucose transport (GLUT-1), glycolytic enzymes (Hexokinase 2) and pH regulation (CA9).

We show that variation in the CFH gene, at sites other than the two potentially functional nsSNPs, I62V and Y402H, is associated with large effects on plasma CFH concentration.

On X centromeres transferred into somatic cell hybrids, H3K9 methylation was not highly enriched at any one site, but was more enriched than the control genes at most sites except site 3 (gamma satellite).

Reports identify cis-acting, expression-altering mutations observed within introns, far upstream of genes, at splicing sites or within microRNA target sites.

For the proteomics analysis, 50 ml cultures of Synechocystis wild type (WT), the mutants constitutively expressing gfp (SN5K.Cgfp, SN8K.Cgfp, SN10K.Cgfp, SN15K.Cgfp and SN16K.Cgfp) and a mutant carrying a promoterless gfp gene at site N15 (SN15K.gfp) were grown in quadruplicate at 30°C under continuous light, until they reached an OD730 ≈ 0.7.

We also examined nucleotide compositional biases in intergenic regions, in RNA genes, and in protein-coding genes at nonsynonymous sites and at 4-fold degenerate synonymous sites (fig. 4 D and E).