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Many of these AR-regulated genes are key regulators of prostate development and maintenance.
These genes are key for the immune system to differentiate between foreign invaders and the body's own tissues.
Non-deepwater rice (i.e., lowland rice) into which SK1 or SK2 had been introduced showed internode elongation in the same way as deepwater rice, indicating that the SK genes are key factors for the escape strategy of deepwater rice under deepwater-flood conditions.
One of the justifications for spending several billion dollars on human genome research is the belief that genes are key determinants of not only rare Mendelian diseases like Huntington's disease or cystic fibrosis but common multi-factorial conditions like cancer, depression, and heart disease.
Runx genes are key regulators of lineage-specific gene expression in major developmental pathways.
As many of these genes are key developmental regulators, the current model holds that PcG protein-mediated repression prevents inappropriate differentiation.
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Two thousand will be extremely obese; 3000 will have neurodevelopmental disorders such as schizophrenia and autism; and 1000 will have rare conditions, such as congenital heart disease, for which it is thought the interplay of multiple genes is key.
Background & Aims: Identification of inflammatory bowel disease (IBD) susceptibility genes is key to understanding pathogenic mechanisms.
Identification of recurrently mutated genes is key to the discovery of important proto-oncogenes and tumour-suppressor genes.
A sufficient level of expression of genes is key to the success of transcriptomic approaches to their identification.
However, comparisons with studies in Drosophila found limited overlap of gene expression patterns, and the handful of commonly regulated genes were key members of canonical immune response pathways.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com