Sentence examples for genes and modulation from inspiring English sources

In concert with this, down-regulation of the PLP2 and XCL2 genes and modulation of the IP3/DAG signaling pathway have been observed.

HU also induces specific patterns of expression for homeostasis related genes and modulation of mRNAs and proteins for ECM deposition, maturation and remodeling which may be key factors for bone maintenance.

Among the changes we highlight induction of transcripts for zinc transporters, differential modulation of transcripts encoding enzymes related to sugar metabolism, depletion of photosynthesis, induction of several defense-related genes, and modulation of transcripts encoding enzymes regulating ROS production.

In addition to its role as an antioxidant, the GSH status of a cell is critical for various other biological events that include transcriptional activation of specific genes and modulation of redox-sensitive signal transduction and hence pro-inflammatory processes during cerebral ischemia [ 22].

Owing to their potential of selective downregulation of gene expression and modulation of gene splicing, ASODNs have attracted attention as promising therapeutic agents in the gene treatment of diseases including cancers [1 3].

Classification by gene ontologies and cluster analysis by k-means of over and under expressed genes provided a broader view of gene expression and modulation in the soybean cotyledons during this process and more specifically during the cotyledonary functional transition from nutrient storage to photosynthesis.

In particular, the reaction of T39-treated plants to pathogen inoculation is associated with enhanced expression of P. viticola-responsive genes and specific modulation of some genes related to defence in resistant grapevines.

In fact, by modulating the expression of different genes, HNE exhibits a wide array of biological activities, including signal transduction, gene expression, and modulation of cell proliferation [ 13].

While miRNAs down-regulate gene expression mostly by destabilization of target messenger RNA [ 8], the regulation of gene expression by lncRNAs appears to be much more complex, involving both activation and repression of gene expression, and modulation of chromatin architecture [ 9].

The three major downstream effects induced by Tet1 and sh-Dnmt1, i.e., DNA demethylation, regulations of gene expression, and modulation of reprogramming, are summarized in Fig. 3d.

Diverse dCas tools have been developed, which constitute a comprehensive toolbox that allows interrogation of gene function and modulation of the cellular behaviors.