Sentence examples for genes and induce from inspiring English sources

A broad general distinction between plants and animals lies in the targeting of endogenously produced miRNAs; in plants, miRNAs are usually perfectly or nearly perfectly complementary to their target genes and induce direct mRNA cleavage by RISC, while animals' miRNAs tend to be more divergent in sequence and induce translational repression.

Its isoforms, which are created by alternative promoters and alternative splicing, have divergent abilities to transactivate p53 reporter genes and induce apoptosis [33] (suggesting a more generalized role).

Moreover, common mechanisms like the recruitment of chromatin remodelling complexes to their target loci are used by both proneural and promyogenic bHLH factors to activate their target genes and induce differentiation [49] [49].

This first comprehensive analysis of gene regulation by PPARγ and PPARα/γ agonists favor the conclusion that glitazones and glitazars share most of their target genes and induce large differential changes in gene profiles in human hepatocytes depending on hepatocyte donor, the compound class and/or individual compound, thereby supporting the occurrence of idiosyncratic toxicity in some patients.

Furthermore, miR-155 has also been shown to down-regulate DNA mismatch repair genes and induce mutator activity (230, 231).

Initially, we hypothesized that genistein would demethylate Wnt inhibitory genes and induce their expression, possibly inhibiting the Wnt pathway.

This suggests that blue light up-regulated the expression of camptothecin biosynthesis-related genes and induced camptothecin biosynthesis.

Therefore, we speculated that mono-ADP-ribosylated modification on H3R117 definitely did some contribution to alter chromatin microenvironment of some specific genes and induced subsequently influence malignant biological behavior of cancer cells.

The HIV DNA delivered by DermaVir to LC expresses most viral regulatory and structural genes and induces T cell-mediated immune responses with broad specificity.

In the same line, EGCG and its methylated metabolite protect against necrosis and apoptosis by suppressing caspase-3 expression, reducing the expression of proapoptotic genes and inducing the anti-apoptotic genes expression [55, 56].

It is enriched in subcutaneous fat, and the ectopic overexpression of HOXC10 suppressed brown fat genes and induced white adipocyte-specific genes with a minimal effect on the pan-adipocyte markers (Ferrannini et al. 2016; Ng et al. 2017).