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Removal of common mRNAs prior to differential display should diminish redundant identification of abundant genes and increase the chance of identifying rare differentially expressed genes.
It is hoped that finding the right genes through careful experimental designs, such as outlined here, will narrow down the number of relevant genes and increase the odds for solving the puzzles of nature, such as ras.
The screening assays can be readily configured for use in future automated high-throughput screening projects to discover potent inhibitors that may be developed into novel adjuvants for antibiotic chemotherapy that moderate the development and transmission of antibiotic resistance genes and increase the antibiotic therapeutic index.
The proHGF treatment produced a more profound decrease in pluripotent genes and increase of differentiation genes than did the other experimental treatments (Figs. 2C, 2D, and S4).
Further gene expression analysis revealed a significant THI-dependent decrease in inflammatory genes and increase in metabolic genes.
Several strategies have been developed to improve the delivery of therapeutic genes and increase the vector uptake by cardiomyocytes.
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Inactivation of RstR results in increased transcription of CTXf genes and increased transmission of both RS1 and CTXf.
Individuals who developed frequent BCCs have an increased prevalence of germline mutations in DNA repair genes and increased malignancy risk.
CGRP (10 -10 -10 -8) M) stimulated BMSC proliferation, up-regulated the expression of osteoblastic genes, and increased ALP activity and mineralization in the BMSCs.
We highlight applications of these networks in predicting tissue-specific molecular response, identifying candidate disease genes, and increasing power by amplifying the disease signal in quantitative genetics data.
Previous studies (including ours) have found an association between variants in DNA repair genes and increased susceptibility to OSCC.
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