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They have added 98 pieces of DNA called loxPsym sequences, which mark individual genes and allow those genes, by the application of an appropriate enzyme, to be excised.
Proponents believe that without private sector funding, funding will not exist to discover additional cancer genes and allow patients to get tested.
In an attempt to compensate for possible differences in base compositions among genes (and allow %Ti to be comparable), each mutation type is divided by the count of its original base (e.g. a substitution from 'A' to 'T' divided by the number of 'A').
As an adjunct tool, morpholino studies provide insight into the molecular function of genes and allow rapid assessment of candidate genes for human muscular dystrophies.
Full-length cDNA and expressed sequence tag (EST) sequences provide direct transcriptional evidence for predicted genes, and allow deduction of their alternative splicing patterns [ 25].
This set of responses includes profound morphological, physiological and metabolic changes, which rely on the induction and repression of numerous genes and allow plants to survive and reproduce under nutrient-deprived conditions.
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In addition, we have developed a multiplexed sgRNA expression strategy that promotes the functional ablation of single genes and allows for combinatorial targeting.
The loss of LexA repressor induces transcription of the SOS genes and allows for further signal induction, inhibition of cell division and an increase in levels of proteins responsible for damage processing.
Down regulation of these genes removes repression of the differentiation genes and allows the ES cells to differentiate.
Manual annotation confirmed expression of 11 known carrot anthocyanin genes and allowed identification of five new ones.
The network of these six Mgs (Fig. 1B) provides a global overview of the functionally overlapping genes and allows to identify hub genes that interconnect groups.
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