Sentence examples for genes activating the from inspiring English sources

These events lead to the HIF1α protein stabilization which can translocate to the nucleus where it forms a complex with HIF1β and recruits CBP/p300 to the promoter of HIF1α target genes, activating the transcription of a vast array of genes responsible of glycolysis, angiogenesis and cell death resistance which are involved in tumor progression.

Therefore, it was expected to find that the predictive subnetwork signature was strongly enriched for genes activating the estrogen receptor (ER) signaling pathway.

These observations demonstrate that MALT1 represses genes activating the aggressive phenotype of carcinoma cells, and suggest that MALT1 acts as a tumour suppressor and that the loss of expression stimulates oral carcinoma progression.

Taken together, these results suggest that genes activating the catabolism of fatty acids are upregulated in the HIGH pìgs, although we have not found direct evidence that genes integrated in the β-oxidation pathway are differentially expressed in the HIGH and LOW groups.

With a qPCR candidate gene approach, they observed an upregulation of genes activating the hypothalamus-pituitary-adrenal axis (including the corticotropin-releasing hormone and its receptor [CRHR1] and NR3C2 encoding the mineralocorticoid receptor) and downregulation of inhibiting genes (eg, androgen receptor).

The binding of p53 to its target genes activates the transcription of genes, such as p21 [16] and IFI16 [17], and repress the transcription of certain anti-apoptotic genes [15].

It is interesting to note that although the majority of the common up-regulated signaling genes activate the immune response, several inhibitory genes are also found for the NF-κB signaling pathway, namely NFKBIB, NFKBIE, TNFAIP3.

Expression of GADD45A and other GADD45-like genes activates the p38/JNK pathway and apoptosis.

Both genes activated the classical NF-κB pathway but used different routes downstream of TAK1 [ 2].

Interestingly, the mutant clones showed weaker expression from GMR > eGFP:: Brdmut, suggesting that the four genes activate the GMR > eGFP:: Brd reporter in parallel to their direct repression of the reporter mediated by miRNA binding.

This assumption is incorrect for sentences like "The inhibition of RbAp46 gene activates the expression of IGFBP-rP1 gene in K562 leukemic cells".