Sentence examples for genes activate the from inspiring English sources

It is interesting to note that although the majority of the common up-regulated signaling genes activate the immune response, several inhibitory genes are also found for the NF-κB signaling pathway, namely NFKBIB, NFKBIE, TNFAIP3.

Interestingly, the mutant clones showed weaker expression from GMR > eGFP:: Brdmut, suggesting that the four genes activate the GMR > eGFP:: Brd reporter in parallel to their direct repression of the reporter mediated by miRNA binding.

Our previous reports have shown that, in contradiction to the prevalent idea that ncRNAs other than classical ncRNAs (tRNA, rRNA, snRNA and snoRNA) downregulate target gene expression, antisense long ncRNAs derived from promoter regions of their respective protein-coding genes activate the expression of those genes via sequence-specific DNA demethylation [ 23, 24].

These events lead to the HIF1α protein stabilization which can translocate to the nucleus where it forms a complex with HIF1β and recruits CBP/p300 to the promoter of HIF1α target genes, activating the transcription of a vast array of genes responsible of glycolysis, angiogenesis and cell death resistance which are involved in tumor progression.

The binding of p53 to its target genes activates the transcription of genes, such as p21 [16] and IFI16 [17], and repress the transcription of certain anti-apoptotic genes [15].

Expression of GADD45A and other GADD45-like genes activates the p38/JNK pathway and apoptosis.

Both genes activated the classical NF-κB pathway but used different routes downstream of TAK1 [ 2].

Therefore, it was expected to find that the predictive subnetwork signature was strongly enriched for genes activating the estrogen receptor (ER) signaling pathway.

Li Y, Deng H, Lv L, Zhang C, Qian L, Xiao J. et al. The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer.

This assumption is incorrect for sentences like "The inhibition of RbAp46 gene activates the expression of IGFBP-rP1 gene in K562 leukemic cells".

Suppose that three genes (A, B, and C) are known to interact in a linear biochemical pathway: The first gene activates the second, which in turn activates the third.