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There is accumulating evidence that Aβ, along with these amyloid-forming polypeptides, can exert a generic toxicity on cells (Baglioni et al., 2006).
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Antiretrovirals with generic alternatives may have toxicity issues, eg, zidovudine and nevirapine.
This paper comprises calculations for plutonium/minor actinides/thorium fuel compositions, their correlated final burn-up and the long term activity and toxicity for a generic pebble bed HTR based on the reference design of the 400 MW PBMR.
The transitional guidance document particularly explains two different generic approaches for the mixture toxicity assessment.
We conclude that fine and ultrafine particle inhalation does not result in toxicity in a generic manner independent of particle composition.
By far, most of the toxicity associated with the generic term "oleander" is due to use and abuse of what is known as yellow oleander or Thevetia peruviana, an entirely different plant than N. oleander.
No mechanism of toxicity can be considered as generic for all NP [126].
Our finding that ferritin offered Aβ-specific rescue from both longevity and eye phenotypes indicates that an important component of Aβ toxicity in vivo is not generic.
This protocol is proposed for the preparation of dispersions for generic acute bioassay applications; its use for chronic toxicity evaluations is beyond the scope of this work and should be validated by use of proper controls.
Tumors stopped growing with no toxicity, whereas the same animals tested with generic methotrexate died".
The TAF-based regimen appears to offer better safety, fewer side effects, and reduced toxicity over TDF-based therapy, which may have generic options available in the near future.
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