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Due to their general nature, generic instruments make comparisons possible between different populations and patients groups.
However, generic instruments generally have a low responsiveness, particularly with PH patients [ 12].
Generic instruments usually address areas concerning general well-being without focusing as much on specific diseases per se.
HRQOL can be assessed using generic instruments, which allow comparison between patients and general populations.
In general, disease specific instruments should be favored against generic instruments, especially due to a higher sensitivity to change.
The same applies to the generic instruments.
Only 5 studies combined (lung) cancer-specific questionnaires with generic instruments.
Only a small number of studies used generic instruments like the EQ-5D.
Three pediatric (one disease specific and two generic) and two (generic) instruments were chosen.
Five studies combined disease-specific (cancer or lung cancer) questionnaires with generic instruments; two times the EQ-5D was applied.
Both are generic instruments.
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