However, this concern is still relevant in the new generation of epoetin agents and generic formulations of epoetins.
Generally the procured price reductions were greater for generic formulations of the various PPIs than for the originator formulations (Table 2).
Generic formulations are by far the most prescribed drugs.
Some specialists, particularly cardiologists and neurologists, are concerned about generic formulations of drugs in which a slight variation could have a serious effect on a patient's health.
It is available in prescription-strength products, including generic formulations, and under brand names like Retin-A Micro, Renova, Avage and Tazorac.
They analyzed different doses of both the branded and generic forms of multiple drugs and reported dose-independent variations in phosphorus content between branded and generic formulations.
However, as the number of drugs examined by Shimoishi et al. was relatively low, the precise nature of branded and generic formulations may require further studies.
"New generic formulations can vary up to 20percentt from the original product," said Judith A. Shuler, a spokeswoman for the Pharmaceutical Manufacturers Association.
In case of paroxetine, all the generic formulations contained lower levels of phosphorus compared with the branded formulations, which was in concurrence to the study by Sherman et al., whereas in case of amlodipine, the results were mixed with few generic formulations having higher levels of phosphorus compared with the branded formulations31,32.
To evaluate discrepancies in doses per bottle, bottle fill volume, and cost among branded and generic formulations of latanoprost.
Study of the relative bioavailability of these generic formulations has yet to be conducted in a Bangladeshi population.
