Sentence examples for generic annotation from inspiring English sources
Annotation of ncRNAs, however, is still not part of generic annotation pipelines of genome or next-generation sequencing data and precise functional annotations of the majority of predictions remain elusive.
By various estimates, at least 30-50% of the genes of any given organism are of unknown function [ 2], incorrectly annotated [ 3, 4], or have only a generic annotation such as 'ATPase' [ 5].
In particular, we are planning on adding two Conditional Random Field-based (23) generic annotation components: one for building a statistical model representing already annotated data, and another for annotating new data based on the previously built model that will be passed to the latter as a parameter.
As a result of this additive strategy, only the most generic annotation terms, those near the root, show the highest scores at the expense of carrying less information.
For this reason, we use the bed file provided by Illumina, not a generic annotation bed file, for example, RefSeq for hg19.
By incorporating the nuID naming scheme into the probe annotation workflow, it is easier to build a generic annotation pipeline that is independent of manufacturer and makes the maintenance of annotations independent of the manufacturer.
Reasons for insignificance include: generic annotations, same function but different annotation, similar but different functions, and completely different function.
The 'probable enzymes' consisted of generic annotations such as 'Methyltransferases' and the precise functions of these enzymes are still unknown.
Generic annotations may have been used at the beginning of the story when GO was still incomplete and with poor coverage of biological knowledge.
We used BINGO [43] with the GO Slim Generic Gene Ontology Annotation [44], which is a set of high-level GO terms.
They include a fumarate reductase possibly involved in anaerobic mitochondrial respiration [ 29], and five proteins with generic functional annotation: acetyltransferase, SAM-dependent methyltransferases, nitroreductase, glycosyl hydrolase and helicase.
