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Creditors argue that at 17% of GDP, Greece's pension system is Europe's costliest and to great degree the generator of its fiscal dysfunction.
FM has been described as a complex hyperalgesic pain syndrome, in which abnormalities of central sensory processing interact with peripheral pain generators and psycho-neuro-endocrine dysfunction [ 5- 7].
It assumes a dysfunction in a central pattern generator in the brainstem that modulates the perception of pain.
Oxidative stress is inseparably linked to mitochondrial dysfunction, as mitochondria are both generators of and targets for reactive species [ 16].
Both the thoracic intervertebral disks and thoracic zygapophyseal joints are thought to be primary pain generators in T4 syndrome based on their pain patterns, suggesting that dysfunction of the costotransverse joint may be implicated as well[ 13].
Periaqueductal gray (PAG) was a center with powerful descending antinociceptive neuronal network [1, 2], and the dysfunction in migraine [3] may be considered as a possible "generator" of migraine attacks [1, 4, 5].
In the electroretinogram (ERG), this complicates interpretation of inner retinal changes as dysfunction may arise from "upstream" neurons or may indicate a direct loss to that neural generator.
Compounds or mutations that cause mitochondrial dysfunction and Parkinson's-like symptoms, such as the respiratory complex I inhibitor rotenone and the superoxide generator paraquat, strongly induce the UPRmt [ 41, 44, 72].
Executive dysfunction . . .
Language dysfunction?
Erectile dysfunction?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com