It also ordered St . JudeMedical to conduct additional studies on both the older generation of leads, called the Riata, and the new generation of Durata leads.
St . Judealso said its product registries are monitoring 11,000 patients with the company's current generation of leads, and it recently announced that it would follow patients in the registry with Optim-coated leads "indefinitely".
Tweek's main revenue model is the generation of leads.
Tweek's main revenue model is the generation of leads to this content.
Combinatorial chemistry is an important component of medicinal chemistry in the generation of leads and the subsequent generation of drug candidates.
They are rarely if ever saturating, and the false negative rate is significant, so they are tools for generation of leads meriting further study 25.
These results will guide the design of a new generation of lead compounds.
Fragment-based drug design (FBDD) is a promising approach for the generation of lead molecules with enhanced activity and especially drug-like properties against therapeutic targets.
From this analysis, we present a schematic approach to the generation of lead-like libraries that can be applied to any starting NP.
Among the rational or semirational design approaches, fragment-based drug discovery (FBDD) has emerged as a useful tool for the generation of lead structures.
Finally, the fusion model was used for the identification of a novel generation of lead-like antiprotozoan compounds by using ligand-based virtual screening of 'available' small molecules (with synthetic feasibility) in our 'in-house' library.
