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The generation, secretion, and regulation of vasoinhibins are embedded into the organizational principle of an axis, which integrates the hypothalamus, the pituitary, and the target tissue microenvironment.
Therefore, the generation, secretion, and regulation of vasoinhibin action are embedded into the organizational principle of an axis, which integrates the hypothalamus, the pituitary, and the target tissue microenvironment.
Thus it appears that generation, secretion, and regulation of vasoinhibin action demonstrate the organizational principle of an axis that integrates the hypothalamus, the pituitary, and the target tissue level (Fig. 1).
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For example, by examining MCF7 breast cancer cells cultured alone or co-cultured with nontransformed fibroblasts, Ko et al. showed that CAFs undergo an autophagic program, leading to the generation and secretion of high glutamine levels into the tumor microenvironment [50].
For example, normal Aβ generation and secretion are dependent upon Tyr682 in vitro.
However, it remains to be seen whether other PSEN mutations have any significant effects on the generation and secretion of Aβ43.
The presence of vasoinhibins in the pituitary gland and plasma reflect their hormonal nature, that is, their generation and secretion by an endocrine gland into the circulation.
In light of the results of the study by Haselton et al. (2010), our results suggest that decreased IDH activity may augment insulin generation or secretion.
Unlike results in OVA-challenged mice alone, PM stimulates the generation and secretion of IL-6 and TNF-α into airways with marked neutrophil infiltration.
Mesenchymal/stromal cells contribute to the survival and replication of hematopoietic stem/progenitor cells (HPC) by adhesion molecules, by way of extracellular matrix generation and secretion of survival factors.
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