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We propose that endosulfan induces the activation of CYP1A in HK which led to the generation of persistent metabolite, ESS, resulting in immunotoxicity.
With a few exceptions, New York City's most sweeping political changes have come through court action, or after at least a generation of persistent political lobbying, not at the public's initiative.
After over a generation of persistent and acrimonious labor shutdowns, the United Steelworkers of America had not called an industrywide strike since 1959; the United Auto Workers had not shut down General Motors since1970.
This environmental prevalence and persistence of the brominated flame retardants, coupled with growing evidence of their potential for harm, present all too familiar parallels with the previous generation of persistent organic pollutants.
It is known, for instance, that excitatory synapses with a slow dynamics (such as synapses mediated by NMDA receptors) may play a relevant role in the generation of persistent activity or up cortical states [17].
These results suggest that an effect of GAD-alum could be mediated by induction of an early Th2-skewed immune response and generation of persistent GAD65-specific cellular and humoral immune responses (15).
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"The overall message, for the first time in a generation, is one of persistent and welcome progress," the journal's editor, Dr. Richard Horton, wrote in a comment accompanying the article, published online on Monday.
We tested at each generation the clustering of persistent genes (Kuiper's test, alpha = 0.05).
Furthermore, flower color provides a useful indicator in advanced-generation hybrid populations of persistent introgression of crop R. sativus alleles.
A couple of the next-big-IPs for the upcoming generation of consoles are "persistent world" games.
Although the sub-apoptotic dose of the combination of VK3 with AA resulted in the appearance of hydroperoxides in the extracellular compartment, intracellular generation of ROS and persistent DNA damage, the cells died only in the presence of α-TOS (c.f. Figure 5).
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