Exact(1)
However, genome-wide generation of disruption mutants in M. loti, in addition to the set of S. meliloti, is also very valuable for several reasons.
Similar(59)
This again results in increased generation of ROS, disruption of the mitochondrial transmembrane potential and cell death (Martinvalet et al, 2008).
It reflects a triumph over two generations of cultural disruption.
It is well documented that antioxidants protect against toxicity caused by reactive oxygen species (ROS) in the prevention of their generation, disruption of attack, scavenging of reactive metabolites and enhancing the resistance to ROS attack on sensitive biological targets [ 38].
These results suggest that the antibacterial mechanism of ZnO action is most likely due to generation of ROS and disruption of bacterial membrane.
Generation of the targeted disruption of the Car9 gene has been previously described by Ortova Gut et al. [ 16].
It has been reported that chemotherapeutic agents induce apoptosis in part by generation of ROS and disruption of redox homeostasis [ 43, 44].
It has also been shown that activation of PDGFR, Src, and Rac1 could be relevant for the generation of Aβ by neurons, and that new targets for therapeutic interventions could be found in this pathway [ 27]; masitinib's inhibition of PDGFR might therefore possibly inhibit Aβ generation through disruption of this pathway.
For the polymorphism rs12510549, the generation or disruption of five different putative binding sites was predicted.
Together, our findings suggest that PAT-induced p62 accumulation might exert pro-oncogenic function through ROS generation and disruption of apoptosis.
ROS generation following toxin exposure appears to occur before complete mitochondrial transmembrane potential (Δ Ψm) dissipation, and all toxins showed a direct relationship between ROS generation and disruption of the Δ Ψm.
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