Sentence examples for generation of derivatives from inspiring English sources

But the unknown unknowns lurking in a new generation of derivatives or in the opaque Chinese financial system could cause nasty surprises.

In this context, the generation of derivatives is of considerable interest.

Following the results we previously reported on a series of ethyl 2-phenylthiomethyl 5-hydroxyindole-3-carboxylate derivatives as 5-lipoxygenase (5-LOX) inhibitors, in order to obtain a more selective compound with respect to the previous generation of derivatives, we decided to modify the structure of the core ligand.

Their configuration and unique mode of stereoselective interaction with tubulin will allow for a better understanding of how antitubulin drugs work and will permit the model-driven chemosynthetic generation of derivatives with optimal activity and stability.

Generation of derivatives of the three germ layers from Ws-4-1 was confirmed by the expression of markers including beta-III tubulin (neuroectoderm) (Figure 2C), nestin (Figure S3A), cytokeratin 18 (endoderm) (Figure 2D), alpha-smooth muscle actin (SMA) (mesoderm) (Figure 2E) and CD31 (Figure S3B).

For the generation of derivatives of the MDA-MB-361 cell line expressing DCD shRNA, we designed shRNA against different regions of the DCD transcript and subcloned them into pLKO-puro lentiviral construct.

Therefore, the objectives of this current study were to: (i) investigate the capability of this bacterial strain to degrade KL, (ii) identify the genes responsible for lignin degradation, (iii) identify the derivatives of this process, and (iv) reconstruct the metabolic pathways involved in degradation of lignin and generation of its derivatives.

Condensation of 5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine-2-carbohydrazide 7 with aromatic aldehydes a k in ethanol at reflux led to the generation of hydrazone derivatives 8a k in 80 92% yield.

By using two distinct biosynthetic pathways, we demonstrate that DNA assembler can perform multiple tasks, including heterologous expression, introduction of single or multiple point mutations, scar-less gene deletion, generation of product derivatives, and creation of artificial gene clusters.

The generation of deletion derivatives from the repair of a DSB occurring inside an element does not require active transposition.

Generation of pneumocandin derivatives with more desirable pharmacological properties via medicinal chemistry approaches has proven difficult [ 16, 17].