The DMTR of the model with HSF and nonuniform heat generation is decreased by 6.57% compared with that with circular-shaped fin.
In this physiologic state, ROS generation is decreased, perhaps because of altered mitochondrial function [ 58].
Thus, superoxide anion-radical generation is decreased by mild uncoupling of respiration and phosphorylation [ 21].
Consequently, we predict that, as the rate of ROS generation is decreased as a result of reduced aerobic metabolism in starved fish, the rate of the cellular antioxidants generation is decreased as well.
Thrombin generation is decreased after CPB, but one molecule of thrombin can cleave up to 1680 molecules of fibrinogen.
One of the important effects of oxidative stress and free radical generation is decreased levels of cellular antioxidants.
Although thrombin generation is decreased after CPB, the balance between thrombin inhibitors such as antithrombin (also decreased after prolonged CPB) and thrombin could be disturbed by adding a drug that generates a 'thrombin burst'.
This mutation, which occurs at the same position as the A673V mutation that causes FAD, is less efficiently cleaved by β-secretase so that Aβ generation is decreased by ~40% [ 10- 12].
10.7554/eLife.09262.007 Figure 4. Spontaneous Ca2+ transient generation is decreased by blocking release of Ca2+ release from internal stores but not by blocking the AMPA receptors, L-type Ca2+ channels or group I mGluRs.
Patients with sepsis have a hypermetabolic and hypercatabolic state, which can be represented by increased oxygen demand on the body tissue and reduced oxygen consumption because of microcirculatory disturbance, thus ATP generation is decreased, the AMP to ATP ratio is increased, and AMPK is activated at last.
Even if the full costs of RES generation were decreasing, this would in turn lead to an increasing burden on the EEG surcharge and represents a fundamental problem for the integration of intermittent RES in the 'energy only' market.
