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In addition, malondialdehyde formation and hydrogen peroxide generation, indicators of oxidative stress, were significantly induced by PFOA treatment in the liver of mice.
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A similar reporting slowdown is occurring on the other first-generation indicators.
The report points out that the paucity of corporate reporting on the first-generation indicators stands in stark contrast to investors' growing interest in building sustainable investment strategies.
Within the developed markets, the recent EU Parliament's directive on non-financial and diversity information will almost certainly lead to an increase in reporting on the seven first-generation indicators.
The report also warns companies of increasing risks if major businesses fail to become more transparent in their performance: "While companies can face barriers in setting up systems to measure and publicly disclose their performance on the seven first-generation indicators, the opportunity cost of opaqueness is rising".
Moreover, by adopting the first generation index as comparison indicator, all the models are initialized in the same way.
With few exceptions, the first, second and our new third generation quality indicators are ultimately measures of aggregate clinical state or course of a facility's residents.
The study by Canadian investment advisory firm Corporate Knights Capital says 97% of companies are failing to provide data on the full set of "first-generation" sustainability indicators - employee turnover, energy, greenhouse gas emissions (GHGs), injury rate, pay equity, waste and water.
Interested readers may consult the technical reports from the Mega-QI study for additional details on the sample recruitment and characteristics, and the rationale and development procedure for second-generation quality indicators.
An important contribution to interRAI's efforts to refine the HCQIs has been the use of European data from the Aged in Home Care (ADHoC) project for both generations of indicators.
The deliverables of the companies included the following measures: Second-generation quality indicator set of the HELIOS Hospital Group [ 12], a private operator of more than 60 hospitals in Germany (3 M and InMed); see also http://www.helios-kliniken.de/medizin/qualitaetsmanagement/transparenz/qualitaetskennzahlen.html for information in German.
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