Sentence examples for generation impaired from inspiring English sources

Over the last years it has become clear that the association among increased ROS generation, impaired endogenous antioxidant systems and low nitric oxide (NO) bioavailability plays a crucial role in the development of the endothelial dysfunction in CKD patients [ 4, 5], predisposing them to long-term complications closely related to atherosclerosis and cardiovascular morbidity [ 6, 7].

In mouse and rat β cells, the SERCA pump is the dominant Ca2+ clearance mechanism [20], [21], thus it is conceivable that reduced ATP generation impairs the Ca2+ clearance function via the SERCA pump, resulting that there is no difference of [Ca2+]i in second-phase between KO and WT cells.

Moreover, excessive oxidative stress by ROS generation impairs endothelium-derived NO bioactivity.

In order to establish whether NO production and O2- generation were impaired in glucose-stressed EPCs, their NO production and O2- generation were compared to that measured in non-stressed EPCs in the presence and absence of 100 μM/mL L-NAME (a non-specific NOS inhibitor) and 10 μM/mL apocynin (an NAD(P H oxidase inhibitor).

In addition, non-verbal generation was impaired although dissociations emerged.

Engineered heart muscles (EHMs) from RBM20-iPSC-CMs showed that not only active force generation was impaired in RBM20-EHMs but also passive stress of the tissue was decreased, suggesting a higher visco-elasticity of RBM20-EHMs.

In addition, glucose-induced ATP generation was impaired.

In conclusion, this study demonstrates β2AR mediated cAMP generation is impaired in asthmatic ASM caused by enhanced cAMP degradation by PDE4, due to increased PDE4 expression.

Innate lymphoid cells drive immune responses against intestinal infections, and their generation is impaired in AhR-deficient mice.

The aim of this study was to investigate whether reflex force generation was impaired in the quadriceps of OA knee patients compared to asymptomatic participants.

Guo et al. demonstrated that Apo A-I knockout mice were more susceptible to septic conditions and had a low capacity for LPS neutralization or clearance, corticosterone generation, and impaired leukocyte recruitment [ 24].