Sentence examples for generation and functioning from inspiring English sources

The gene maps to chromosome Xp11.23 and encodes a 431 amino acid protein, also named scurfin, required for the generation and functioning of CD4+CD25+ regulatory T lymphocytes.

The synthesis equations used for motion generation and function generation are established.

Regulatory T cells (Treg) can interfere with the generation and function of anti-tumor immune effectors.

The cooperative binding of transcription factors regulates the differentiation of T cells as well as the generation and function of B cells and dendritic cells.

Although TAM interferes with normal T lymphocyte generation and function, contributing to tumor tolerance as a tumor-trophic cell lineage, some immunological factors are able to reverse these TAM-specific immunosuppressive properties.

Mathematical models are crucial to understanding the mechanisms underlying the generation and function of these oscillations.

In contrast to intestinal CD4+ regulatory T cells (Tregs), the generation and function of immunomodulatory intestinal CD8+ T cells is less well defined.

Although the aim of our study was to evaluate generation and functions of BMDMs from cryopreserved BM cells, we also preformed preliminary studies to assess the application of the method for generation of bone marrow-derived dendritic cells (BMDCs).

For instance, some defects in the generation and function of DA neurons are obviously part of the Parkinson's disease phenotype but have also been reported in Alzheimer's disease.

Nevertheless, we infer from these results that the down-regulated Wnt signaling pathway demonstrated in this study may contribute to defective generation and function of DA neurons, possibly by down-regulating downstream transcription factors such as Lmx1a and En-1 (Figure 2) and others whose expression is necessary for effective generation of DA neurons [18] [21], [30].

We also demonstrate that two key transcription factor genes known to be regulated by Wnt signaling and to be vital for the generation and function of dopaminergic neurons; i.e., Lmx1a and Engrailed 1, are down-regulated in the HPRT knockdown SH-SY5Y cells.