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Sequence generation and allocation concealment were generally poorly described.
For sequence generation and allocation concealment, the majority of trials (27 and respectively 28) did not provide any information to enable assessment.
Only one study [23] had both sequence generation and allocation concealment rating of "high risk of bias".
ANZCTR, Clinical Trials Registry – India, and the Chinese Clinical Trial Register were the only registries that offered specific fields for random sequence generation and allocation concealment.
The randomisation procedure ensured adequate sequence generation and allocation concealment.
Reporting of sequence generation and allocation concealment was often unclear.
Sequence generation and allocation concealment were poorly reported.
Selection bias: random sequence generation and allocation concealment.
Almost all studies were randomised with appropriate methods for sequence generation, and allocation was well concealed.
The following domains will be assessed: Selection bias: random sequence generation and allocation concealment.
All but one presented description of random sequence generation and allocation concealment.
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